SGLT2 inhibitors: Cost Comparison
SGLT2 (sodium-glucose cotransporter-2) inhibitors lower blood sugar by making the kidneys remove glucose in urine, and are also used in heart failure and chronic kidney disease.
Across these 2 drugs, average Medicare Part D spending per dosage unit ranges from $18.31 (Farxiga) to $18.94 (Jardiance) for calendar year 2024. Figures are real CMS open data, in US dollars.
How much do sglt2 inhibitors cost in the US?
As of calendar year 2024, average Medicare Part D spending per dosage unit for these 2 sglt2 inhibitors ranged from $18.31 (Farxiga) to $18.94 (Jardiance), per CMS open data. These are Medicare program spending figures per billing unit — not pharmacy cash prices, and not medical advice.
| Drug | Generic (active ingredient) | Avg Part D spending / dosage unit | 2024 Part D claims |
|---|---|---|---|
| Jardiance | Empagliflozin | $18.94 | 11,368,280 |
| Farxiga | Dapagliflozin Propanediol | $18.31 | 5,634,650 |
Figures are CMS’s own published Medicare Part D spending values (field Avg_Spnd_Per_Dsg_Unt_Wghtd_2024), reported unchanged. The most-prescribed drug in this group in 2024 was Jardiance (11.4 million claims). View the full dataset on CMS data.cms.gov.
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Jardiance
EmpagliflozinThis is average Medicare Part D program spending per dosage unit, not a pharmacy cash price or a per-prescription cost. Information only — not medical advice and not a price quote.
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Frequently asked questions
- Which sglt2 inhibitors are compared here?
- This page compares 2 sglt2 inhibitors from the CMS Medicare Part D dataset (calendar year 2024): Jardiance, Farxiga. Each is shown with its real average Medicare Part D spending per dosage unit in US dollars.
- What is the cheapest sglt2 inhibitor by Medicare spending per unit?
- Among these drugs, Farxiga had the lowest average Medicare Part D spending per dosage unit at $18.31 (calendar year 2024), and Jardiance the highest at $18.94. This is program spending per billing unit, not a retail price, and dosage units differ between drugs.
- Is this the price I would pay for sglt2 inhibitors?
- No. These figures are average Medicare Part D program spending per dosage unit from CMS open data, not a pharmacy cash price or per-prescription cost. What you pay depends on your pharmacy, insurance, manufacturer, dose and region. This is information only, not medical advice.
- Can a GeraClinic clinician help with type 2 diabetes, heart failure and chronic kidney disease?
- A GeraClinic clinician can review your medication for type 2 diabetes, heart failure and chronic kidney disease, explain the options, and issue or renew a prescription online where clinically appropriate. GeraClinic only lists independently verified, licensed clinicians.
Need help with type 2 diabetes, heart failure and chronic kidney disease?
A GeraClinic clinician can review your medication, explain the options, and issue or renew a prescription online where clinically appropriate — without travelling to a clinic.
Contains public sector information published by U.S. Centers for Medicare & Medicaid Services (CMS) and licensed under the U.S. Government Works / Public Domain. Source: CMS Medicare Part D Spending by Drug (calendar year 2024, published 2026-06-25).
Informational/educational only — not a substitute for professional medical advice; a clinician interprets results.