Blood thinners (anticoagulants & antiplatelets): Cost Comparison
Blood thinners reduce the blood’s ability to clot. This group spans direct oral anticoagulants (apixaban, rivaroxaban), the older anticoagulant warfarin, and the antiplatelet clopidogrel — different mechanisms, all used to prevent clots.
Across these 4 drugs, average Medicare Part D spending per dosage unit ranges from $0.1367 (Warfarin Sodium) to $17.68 (Xarelto) for calendar year 2024. Figures are real CMS open data, in US dollars.
How much do blood thinners (anticoagulants & antiplatelets) cost in the US?
As of calendar year 2024, average Medicare Part D spending per dosage unit for these 4 blood thinners (anticoagulants & antiplatelets) ranged from $0.1367 (Warfarin Sodium) to $17.68 (Xarelto), per CMS open data. These are Medicare program spending figures per billing unit — not pharmacy cash prices, and not medical advice.
| Drug | Generic (active ingredient) | Avg Part D spending / dosage unit | 2024 Part D claims |
|---|---|---|---|
| Eliquis | Apixaban | $9.637 | 24,061,332 |
| Clopidogrel | Clopidogrel Bisulfate | $0.1766 | 13,582,037 |
| Xarelto | Rivaroxaban | $17.68 | 6,660,246 |
| Warfarin Sodium | Warfarin Sodium | $0.1367 | 4,665,402 |
Figures are CMS’s own published Medicare Part D spending values (field Avg_Spnd_Per_Dsg_Unt_Wghtd_2024), reported unchanged. The most-prescribed drug in this group in 2024 was Eliquis (24.1 million claims). View the full dataset on CMS data.cms.gov.
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Eliquis
ApixabanThis is average Medicare Part D program spending per dosage unit, not a pharmacy cash price or a per-prescription cost. Information only — not medical advice and not a price quote.
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Frequently asked questions
- Which blood thinners (anticoagulants & antiplatelets) are compared here?
- This page compares 4 blood thinners (anticoagulants & antiplatelets) from the CMS Medicare Part D dataset (calendar year 2024): Eliquis, Clopidogrel, Xarelto, Warfarin Sodium. Each is shown with its real average Medicare Part D spending per dosage unit in US dollars.
- What is the cheapest blood thinners (anticoagulants & antiplatelets) by Medicare spending per unit?
- Among these drugs, Warfarin Sodium had the lowest average Medicare Part D spending per dosage unit at $0.1367 (calendar year 2024), and Xarelto the highest at $17.68. This is program spending per billing unit, not a retail price, and dosage units differ between drugs.
- Is this the price I would pay for blood thinners (anticoagulants & antiplatelets)?
- No. These figures are average Medicare Part D program spending per dosage unit from CMS open data, not a pharmacy cash price or per-prescription cost. What you pay depends on your pharmacy, insurance, manufacturer, dose and region. This is information only, not medical advice.
- Can a GeraClinic clinician help with preventing dangerous blood clots, stroke and DVT?
- A GeraClinic clinician can review your medication for preventing dangerous blood clots, stroke and DVT, explain the options, and issue or renew a prescription online where clinically appropriate. GeraClinic only lists independently verified, licensed clinicians.
Need help with preventing dangerous blood clots, stroke and DVT?
A GeraClinic clinician can review your medication, explain the options, and issue or renew a prescription online where clinically appropriate — without travelling to a clinic.
Contains public sector information published by U.S. Centers for Medicare & Medicaid Services (CMS) and licensed under the U.S. Government Works / Public Domain. Source: CMS Medicare Part D Spending by Drug (calendar year 2024, published 2026-06-25).
Informational/educational only — not a substitute for professional medical advice; a clinician interprets results.