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Clinical reference calculator · GeraClinic

Corrected Sodium for Hyperglycaemia Calculator

Hyperglycaemia dilutes serum sodium, so the measured value underestimates the true sodium. The correction adds a factor times the glucose excess over 100 mg/dL: the classic Katz factor is 1.6 and the Hillier factor is 2.4 mmol/L per 100 mg/dL of glucose above normal.

Quick answer

High blood glucose pulls water into the bloodstream and dilutes sodium, so the measured value reads low. The corrected sodium adds a factor times the glucose excess over 100 mg/dL: corrected Na = measured Na + factor × (glucose − 100) ÷ 100. The Katz factor is 1.6 and the Hillier factor is 2.4 mmol/L per 100 mg/dL.

Corrected sodium inputs

Correction is applied to glucose above 100 mg/dL only. No correction below 100 mg/dL.

How to use the Corrected Sodium calculator

  1. 1Enter the measured sodium and glucose. Enter the measured serum sodium (mmol/L) and the blood glucose (mg/dL).
  2. 2Read both corrected values. The tool applies both the classic Katz factor of 1.6 and the Hillier factor of 2.4 and shows the two corrected sodium estimates.
  3. 3Interpret with a clinician. The corrected sodium reflects the patient’s true sodium status once glucose is normalised; treatment of hyperglycaemia and any true sodium disturbance is decided by a clinician.

Medical disclaimer: This is general health information, not medical advice. It does not diagnose or treat any condition, and the results are estimates based on public reference formulas. Always consult a qualified doctor about your individual health. If you think you may have a medical emergency, contact your local emergency services immediately.

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Frequently asked questions

Why does high glucose lower the measured sodium?

Glucose is osmotically active, so marked hyperglycaemia draws water from cells into the blood, diluting the sodium concentration. This is "pseudohyponatraemia" of hyperglycaemia: the measured sodium is low even though total body sodium may be normal.

Should I use the 1.6 or 2.4 correction factor?

Both are used. The classic Katz factor (1.6 mmol/L per 100 mg/dL of glucose above 100) is the traditional choice; Hillier’s later work suggested 2.4 is more accurate, especially at very high glucose levels. This tool shows both so a clinician can choose.

Does the correction change how hyponatraemia is treated?

It can. Knowing the corrected sodium helps distinguish dilutional pseudohyponatraemia (which improves as glucose is treated) from a true sodium disturbance that needs separate management. The interpretation belongs to a clinician.

Is my data stored?

No. The calculator runs entirely in your browser; nothing you enter is sent to a server.

Sources & validation

This calculator reproduces the published Corrected Sodium score, validated for estimating true serum sodium in the presence of hyperglycaemia.

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